STK3+STK4 Antibody, Cy7 Conjugated

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Catalog number: bs-7599R-Cy7
Price: 326 €
Supplier: acr
Product name: STK3+STK4 Antibody, Cy7 Conjugated
Quantity: 30 Вµl
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More details :

Long name: Cy7 Conjugated, STK3+STK4 Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Cy7
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: STK3+STK4
Specificity: This is a highly specific antibody against STK3+STK4
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen_range: 110-150/491
Subcellular location: Helical
Source: KLH conjugated synthetic peptide derived from human STK3
Gene ID number: 6788, 6789
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis, The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation, following caspase-cleavage, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, pro-apoptotic kinase which, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ, Stress-activated
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 743nm/767nm
Synonyms: MST2 KRS1
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated: These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene target: STK3+STK4 Conjugated
Short name: Conjugated, STK3+STK4 Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: Cy7
Alternative name: cyanine 7 coupled, serine/threonine kinase 3+serine/threonine kinase 4 (Antibody to)
Alternative technique: antibodies
Alternative to gene target: KRS1 and MST2, KRS2 and MST1 and TIIAC and YSK3, STK3 and IDBG-30072 and ENSG00000104375 and 6788, STK3 and IDBG-645151 and ENSBTAG00000026234 and 533815, STK4 and IDBG-642847 and ENSBTAG00000003257 and 514886, STK4 and IDBG-77184 and ENSG00000101109 and 6789, Stk3 and IDBG-134139 and ENSMUSG00000022329 and 56274, Stk4 and IDBG-212019 and ENSMUSG00000018209 and 58231, nuclei, nuclei, serine/threonine kinase 4, this GO :0000287 and magnesium ion binding and molecular function this GO :0000902 and cell morphogenesis and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001841 and neural tube formation and biological process this GO :0003157 and endocardium development and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007417 and central nervous system development and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016772 and transferase activity, this GO :0000287 and magnesium ion binding and molecular function this GO :0001841 and neural tube formation and biological process this GO :0003157 and endocardium development and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007417 and central nervous system development and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016772 and transferase activity, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008134 : transcription factor binding and also this GO :0016772 : transferase activity, this GO :0000287 : magnesium ion binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005524 : ATP binding, this GO :0008134 : transcription factor binding, this GO :0016772 : transferase activity, this GO :0016772 : transferase activity, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0043539 : protein serine/threonine kinase activator activity, this GO :0043539 : protein serine/threonine kinase activator activity, this GO :0046983 : protein dimerization activity, this GO :0046983 : protein dimerization activity, transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043539 : protein serine/threonine kinase activator activity and also this GO :0046983 : protein dimerization activity, transferring phosphorus-containing groups and also this GO :0043539 : protein serine/threonine kinase activator activity and also this GO :0046983 : protein dimerization activity, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030216 and keratinocyte differentiation and biological process this GO :0035329 and hippo signaling and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043539 and protein serine/threonine kinase activator activity and molecular function this GO :0046621 and negative regulation of organ growth and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0060215 and primitive hemopoiesis and biological process this GO :0060706 and cell differentiation involved in embryonic placenta development and biological process this GO :0071902 and positive regulation of protein serine/threonine kinase activity and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0097284 and hepatocyte apoptotic process and biological process this GO :1902043 and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process, transferring phosphorus-containing groups and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0035329 and hippo signaling and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043539 and protein serine/threonine kinase activator activity and molecular function this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046621 and negative regulation of organ growth and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0060215 and primitive hemopoiesis and biological process this GO :0060706 and cell differentiation involved in embryonic placenta development and biological process this GO :0071902 and positive regulation of protein serine/threonine kinase activity and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0097284 and hepatocyte apoptotic process and biological process this GO :1902043 and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process, serine/threonine kinase 3
Identity: 11406
Gene: STK3 | More about : STK3
Long gene name: serine/threonine kinase 3
Synonyms gene name: serine/threonine kinase 3 (Ste20, yeast homolog)
Locus: 8q22, 2
Discovery year: 1997-10-09
GenBank acession: BC010640
Entrez gene record: 6788
Pubmed identfication: 8816758
RefSeq identity: NM_006281
Havana BLAST/BLAT: OTTHUMG00000164651

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