| Long name: |
ALEXA FLUOR 647 Conjugated, CPB2 Polyclonal Antibody |
| Also known as: |
Anti-CPB2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CPB2 |
| Specificity: |
This is a highly specific antibody against CPB2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CPB2 |
| Gene ID Number: |
1361 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, Being activated by thrombin-thrombomodulin complex during blood coagulation, Elevated concentration in blood is considered as a risk factor for venous thrombosis, High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease, It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues, The concentration in plasma of healthy people is 5-10 ug/ml, This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot, and decreased levels are found in chronic liver disease, it exerts carboxypeptidase activity, pI 5, which is necessary for plasminogen binding to fibrin, 0), This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
CPU PCPB TAFI |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the CPB2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
CPB2 |
| Short name: |
CPB2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, CPB2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2300 |
| Gene: |
CPB2 |
More about : CPB2 |
| Long gene name: |
carboxypeptidase B2 |
| Synonyms gene name: |
carboxypeptidase B2 (plasma, carboxypeptidase U) carboxypeptidase B2 (plasma) |
| Synonyms name: |
thrombin-activatable fibrinolysis inhibitor carboxypeptidase U plasma carboxypeptidase B carboxypeptidase R |
| Locus: |
13q14, 13 |
| Discovery year: |
1992-04-10 |
| GenBank acession: |
M75106 |
| Entrez gene record: |
1361 |
| Pubmed identfication: |
1939207 1427879 |
| RefSeq identity: |
NM_001872 |
| Classification: |
Carboxypeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000016867 |