| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Carboxypeptidase B2 / CPB2 / TAFI |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, Western blot |
| Recommended dilutions: |
5-1ug/ml, IHC (FFPE): 1-2ug/ml, Western blot: 0 |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This Carboxypeptidase B2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q96IY4 |
| Purity: |
Antigen affinity |
| Description: |
Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen, CPB2 exhibits carboxypeptidase activity, CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen, When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, also known as carboxypeptidase U (CPU), in humans, is an enzyme that, is encoded by the gene CPB2, plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), Carboxypeptidase B2 (CPB2) |
| Immunogen: |
Amino acids K166-D388 from the human protein were used as the immunogen for the Carboxypeptidase B2 antibody |
| Storage: |
After reconstitution, Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, store at 4oC, the Carboxypeptidase B2 antibody may be kept for up to one month refrigerated at +4 degrees C, For long-term, Prior to reconstitution |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Carboxypeptidase B2 / CPB2 / TAFI |
| Short name: |
Carboxypeptidase B2 Antibody / CPB2 / TAFI |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Carboxypeptidase B2 (Antibody to) / CPB2 / TAFI |
| Alternative technique: |
antibodies |
| Identity: |
2300 |
| Gene: |
CPB2 |
More about : CPB2 |
| Long gene name: |
carboxypeptidase B2 |
| Synonyms gene name: |
carboxypeptidase B2 (plasma, carboxypeptidase U) carboxypeptidase B2 (plasma) |
| Synonyms: |
CPU PCPB TAFI |
| Synonyms name: |
thrombin-activatable fibrinolysis inhibitor carboxypeptidase U plasma carboxypeptidase B carboxypeptidase R |
| Locus: |
13q14, 13 |
| Discovery year: |
1992-04-10 |
| GenBank acession: |
M75106 |
| Entrez gene record: |
1361 |
| Pubmed identfication: |
1939207 1427879 |
| RefSeq identity: |
NM_001872 |
| Classification: |
Carboxypeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000016867 |