| Long name: |
ALEXA FLUOR 647 Conjugated, PRAME Polyclonal Antibody |
| Also known as: |
Anti-PRAME PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PRAME |
| Specificity: |
This is a highly specific antibody against PRAME |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
180-227/509 |
| Subcellular location: |
Cell membrane, Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRAME |
| Gene ID Number: |
23532 |
| Swiss Prot: |
P78395 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Prevents retinoic acid-induced cell proliferation arrest, RARB and RARG, differentiation and apoptosis, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, Functions as a transcriptional repressor |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
CT130 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the PRAME Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
PRAME |
| Short name: |
PRAME Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, preferentially expressed antigen in melanoma (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CT130 and MAPE and OIP-4 and OIP4, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0030154 and cell differentiation and biological process this GO :0040008 and regulation of growth and biological process this GO :0042974 and retinoic acid receptor binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0048387 and negative regulation of retinoic acid receptor signaling pathway and biological process, PRAME and IDBG-2240 and ENSG00000185686 and 23532, nuclei, retinoic acid receptor binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0042974 : retinoic acid receptor binding, this GO :0042974 : retinoic acid receptor binding, preferentially expressed antigen in melanoma |
| Identity: |
9336 |
| Gene: |
PRAME |
More about : PRAME |
| Long gene name: |
preferentially expressed antigen in melanoma |
| Synonyms gene: |
MAPE |
| Synonyms name: |
cancer/testis antigen 130 |
| Locus: |
22q11, 22 |
| Discovery year: |
1996-06-21 |
| GenBank acession: |
U65011 |
| Entrez gene record: |
23532 |
| Pubmed identfication: |
9047241 10591208 |
| RefSeq identity: |
NM_206953 |
| Classification: |
PRAME family |
| Havana BLAST/BLAT: |
OTTHUMG00000151172 |