| Long name: |
ALEXA FLUOR 350 Conjugated, PRAME Polyclonal Antibody |
| Also known as: |
Anti-PRAME PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PRAME |
| Specificity: |
This is a highly specific antibody against PRAME |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
180-227/509 |
| Subcellular location: |
Cell membrane, Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRAME |
| Gene ID Number: |
23532 |
| Swiss Prot: |
P78395 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Prevents retinoic acid-induced cell proliferation arrest, RARB and RARG, differentiation and apoptosis, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, Functions as a transcriptional repressor |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
CT130 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
PRAME |
| Short name: |
PRAME Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, preferentially expressed antigen in melanoma (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CT130 and MAPE and OIP-4 and OIP4, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0030154 and cell differentiation and biological process this GO :0040008 and regulation of growth and biological process this GO :0042974 and retinoic acid receptor binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0048387 and negative regulation of retinoic acid receptor signaling pathway and biological process, PRAME and IDBG-2240 and ENSG00000185686 and 23532, nuclei, retinoic acid receptor binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0042974 : retinoic acid receptor binding, this GO :0042974 : retinoic acid receptor binding, preferentially expressed antigen in melanoma |
| Identity: |
9336 |
| Gene: |
PRAME |
More about : PRAME |
| Long gene name: |
preferentially expressed antigen in melanoma |
| Synonyms gene: |
MAPE |
| Synonyms name: |
cancer/testis antigen 130 |
| Locus: |
22q11, 22 |
| Discovery year: |
1996-06-21 |
| GenBank acession: |
U65011 |
| Entrez gene record: |
23532 |
| Pubmed identfication: |
9047241 10591208 |
| RefSeq identity: |
NM_206953 |
| Classification: |
PRAME family |
| Havana BLAST/BLAT: |
OTTHUMG00000151172 |