| Long name: |
FITC Conjugated, RAB7 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RAB7 |
| Specificity: |
This is a highly specific antibody against RAB7 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
110-160/207 |
| Source: |
KLH conjugated synthetic peptide derived from human RAB7 |
| Gene ID number: |
7879 |
| Swiss Prot: |
P51149 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also involved in regulation of some specialized endosomal membrane trafficking, Controls the endosomal trafficking and neurite outgrowth signaling of NTRK1/TRKA, Governs early-to-late endosomal maturation, In concert with RAC1, Microbial pathogens possess survival strategies governed by RAB7A, Mycobacterium), Plays a central role, Plays a role in the fusion of phagosomes with lysosomes, Plays a role in the maturation and acidification of phagosomes that engulf pathogens, Plays important roles in microbial pathogen infection and survival, Regulates the endocytic trafficking of the EGF-EGFR complex by regulating its lysosomal degradation, Salmonella) and sometimes by excluding RAB7A function (e, and endosome-lysosome transport through different protein-protein interaction cascades, as well as in participating in the life cycle of viruses, but also in many other cellular and physiological events, microtubule minus-end as well as plus-end directed endosomal migration and positioning, neurotrophin transport in the axons of neurons and lipid metabolism, not only in endosomal traffic, nutrient-transportor mediated nutrient uptake, pathogen-induced phagosomes (or vacuoles) and autophagosomes, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts, sometimes by employing RAB7A function (e, such as S, such as growth-factor-mediated cell signaling, such as maturation of melanosomes, Key regulator in endo-lysosomal trafficking, aureus and M, g, g, tuberculosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RAB7 Conjugated |
| Short name: |
FITC Conjugated, RAB7 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, RAB7 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9788 |
| Gene: |
RAB7A |
More about : RAB7A |
| Long gene name: |
RAB7A, member RAS oncogene family |
| Synonyms gene: |
RAB7 |
| Synonyms gene name: |
RAB7, member RAS oncogene family |
| Locus: |
3q21, 3 |
| Discovery year: |
1999-03-24 |
| GenBank acession: |
X93499 |
| Entrez gene record: |
7879 |
| Pubmed identfication: |
9126495 9428630 |
| Classification: |
RAB, member RAS oncogene GTPases |
| Havana BLAST/BLAT: |
OTTHUMG00000159812 |
| Locus Specific Databases: |
LRG_266 |