| Long name: |
Cy5, 5 Conjugated, RAB7 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RAB7 |
| Specificity: |
This is a highly specific antibody against RAB7 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
110-160/207 |
| Source: |
KLH conjugated synthetic peptide derived from human RAB7 |
| Gene ID number: |
7879 |
| Swiss Prot: |
P51149 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also involved in regulation of some specialized endosomal membrane trafficking, Controls the endosomal trafficking and neurite outgrowth signaling of NTRK1/TRKA, Governs early-to-late endosomal maturation, In concert with RAC1, Microbial pathogens possess survival strategies governed by RAB7A, Mycobacterium), Plays a central role, Plays a role in the fusion of phagosomes with lysosomes, Plays a role in the maturation and acidification of phagosomes that engulf pathogens, Plays important roles in microbial pathogen infection and survival, Regulates the endocytic trafficking of the EGF-EGFR complex by regulating its lysosomal degradation, Salmonella) and sometimes by excluding RAB7A function (e, and endosome-lysosome transport through different protein-protein interaction cascades, as well as in participating in the life cycle of viruses, but also in many other cellular and physiological events, microtubule minus-end as well as plus-end directed endosomal migration and positioning, neurotrophin transport in the axons of neurons and lipid metabolism, not only in endosomal traffic, nutrient-transportor mediated nutrient uptake, pathogen-induced phagosomes (or vacuoles) and autophagosomes, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts, sometimes by employing RAB7A function (e, such as S, such as growth-factor-mediated cell signaling, such as maturation of melanosomes, Key regulator in endo-lysosomal trafficking, aureus and M, g, g, tuberculosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
RAB7 Conjugated |
| Short name: |
Conjugated, RAB7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, RAB7 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9788 |
| Gene: |
RAB7A |
More about : RAB7A |
| Long gene name: |
RAB7A, member RAS oncogene family |
| Synonyms gene: |
RAB7 |
| Synonyms gene name: |
RAB7, member RAS oncogene family |
| Locus: |
3q21, 3 |
| Discovery year: |
1999-03-24 |
| GenBank acession: |
X93499 |
| Entrez gene record: |
7879 |
| Pubmed identfication: |
9126495 9428630 |
| Classification: |
RAB, member RAS oncogene GTPases |
| Havana BLAST/BLAT: |
OTTHUMG00000159812 |
| Locus Specific Databases: |
LRG_266 |