| Long name: |
Biotin Conjugated, DICER1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DICER1 |
| Specificity: |
This is a highly specific antibody against DICER1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1330-1380/1922 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human DICER1 |
| Gene ID number: |
23405 |
| Swiss Prot: |
Q9UPY3 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, Gene silencing mediated by siRNAs, SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation, The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance, producing respectively short interfering RNAs (siRNA) and mature microRNAs, Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Dicer KIAA0928 K12H4, 8-LIKE HERNA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DICER1 Conjugated |
| Short name: |
Conjugated, DICER1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, DICER1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17098 |
| Gene: |
DICER1 |
More about : DICER1 |
| Long gene name: |
dicer 1, ribonuclease III |
| Synonyms gene: |
MNG1 |
| Synonyms gene name: |
Dcr-1 homolog (Drosophila) multinodular goitre 1 dicer 1, Dicer1, ribonuclease type III |
| Synonyms name: |
dicer 1, double-stranded RNA-specific endoribonuclease |
| Locus: |
14q32, 13 |
| Discovery year: |
2002-05-09 |
| GenBank acession: |
AB028449 |
| Entrez gene record: |
23405 |
| Pubmed identfication: |
10051563 10786632 21205968 |
| Classification: |
RNA helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000166134 |
| Locus Specific Databases: |
LRG_492 |