| Long name: |
DICER1 Primary Polyclonal Antibody |
| Also known as: |
DICER1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DICER1 |
| Specificity: |
This is a highly specific antibody against DICER1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1330-1380/1922 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DICER1 |
| Gene ID number: |
23405 |
| Swiss Prot: |
Q9UPY3 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, Gene silencing mediated by siRNAs, SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation, The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance, producing respectively short interfering RNAs (siRNA) and mature microRNAs, Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DICER1, Dicer, Dicer1e, Endoribonuclease Dicer, HERNA, Helicase MOI, Helicase with RNase motif, K12H4, KIAA0928, MNG1, RMSE2, 8-LIKE, DCR1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DICER1 |
| Short name: |
DICER1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DICER1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17098 |
| Gene: |
DICER1 |
More about : DICER1 |
| Long gene name: |
dicer 1, ribonuclease III |
| Synonyms gene: |
MNG1 |
| Synonyms gene name: |
Dcr-1 homolog (Drosophila) multinodular goitre 1 dicer 1, Dicer1, ribonuclease type III |
| Synonyms: |
Dicer KIAA0928 K12H4, 8-LIKE HERNA |
| Synonyms name: |
dicer 1, double-stranded RNA-specific endoribonuclease |
| Locus: |
14q32, 13 |
| Discovery year: |
2002-05-09 |
| GenBank acession: |
AB028449 |
| Entrez gene record: |
23405 |
| Pubmed identfication: |
10051563 10786632 21205968 |
| Classification: |
RNA helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000166134 |
| Locus Specific Databases: |
LRG_492 |