| Long name: |
ALEXA FLUOR 488 Conjugated, DICER1 Polyclonal Antibody |
| Also known as: |
Anti-DICER1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DICER1 |
| Specificity: |
This is a highly specific antibody against DICER1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1330-1380/1922 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DICER1 |
| Gene ID Number: |
23405 |
| Swiss Prot: |
Q9UPY3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, Gene silencing mediated by siRNAs, SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation, The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance, producing respectively short interfering RNAs (siRNA) and mature microRNAs, Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
Dicer KIAA0928 K12H4, 8-LIKE HERNA |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DICER1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
DICER1 |
| Short name: |
DICER1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, DICER1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17098 |
| Gene: |
DICER1 |
More about : DICER1 |
| Long gene name: |
dicer 1, ribonuclease III |
| Synonyms gene: |
MNG1 |
| Synonyms gene name: |
Dcr-1 homolog (Drosophila) multinodular goitre 1 dicer 1, Dicer1, ribonuclease type III |
| Synonyms name: |
dicer 1, double-stranded RNA-specific endoribonuclease |
| Locus: |
14q32, 13 |
| Discovery year: |
2002-05-09 |
| GenBank acession: |
AB028449 |
| Entrez gene record: |
23405 |
| Pubmed identfication: |
10051563 10786632 21205968 |
| Classification: |
RNA helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000166134 |
| Locus Specific Databases: |
LRG_492 |