| Long name: |
ALEXA FLUOR 488 Conjugated, Emerin Polyclonal Antibody |
| Also known as: |
Anti-Emerin PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Emerin |
| Specificity: |
This is a highly specific antibody against Emerin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Emerin |
| Gene ID Number: |
2010 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway, Association of EMD with the viral DNA requires the presence of BAF and viral integrase, EMD and BAF are cooperative cofactors of HIV-1 infection, Inhibits beta-catenin activity by preventing its accumulation in the nucleus, Links centrosomes to the nuclear envelope via a microtubule association, Required for proper localization of non-farnesylated prelamin-A/C, Skeletal muscle, Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments, The association of viral DNA with chromatin requires the presence of BAF and EMD, colon, heart, ovary and pancreas, testis, Stabilizes and promotes the formation of a nuclear actin cortical network, Tissue specificity |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
STA LEMD5 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Emerin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Emerin |
| Short name: |
Emerin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Emerin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3331 |
| Gene: |
EMD |
More about : EMD |
| Long gene name: |
emerin |
| Synonyms gene name: |
Emery-Dreifuss muscular dystrophy |
| Synonyms name: |
LEM domain containing 5 |
| Locus: |
Xq28 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X82434 |
| Entrez gene record: |
2010 |
| Classification: |
LEM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000033186 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy Pages UMD Locus Specific Databases Leiden Muscular Dystrophy pages Mental Retardation database LRG_745 |