| Long name: |
HRP Conjugated, ApoER2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ApoER2 |
| Specificity: |
This antibody will detect both the membrane bound and the secreted isoform variants of this protein, This is a highly specific antibody against ApoER2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
848-898/963 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human ApoER2 |
| Gene ID number: |
7804 |
| Swiss Prot: |
Q14114 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature, Binds the endoplasmic reticulum resident receptor-associated protein (RAP), Highly expressed in the initial segment of the epididymis, LRP8 has higher affinity for Reelin than VLDLR, LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development, LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, May also function as an endocytic receptor, Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons, by binding to DAB1 on its cytoplasmic tail, two proteins required for sperm maturation, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
APOER2, Apolipoprotein E receptor 2, HSZ75190, LRP-8, LRP8, Low-density lipoprotein receptor-related protein 8, MCI1 |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
ApoER2 Conjugated |
| Short name: |
Conjugated, ApoER2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, ApoER2 (Antibody to) |
| Alternative technique: |
antibodies |