| Long name: |
ALEXA FLUOR 647 Conjugated, ApoER2 Polyclonal Antibody |
| Also known as: |
Anti-ApoER2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ApoER2 |
| Specificity: |
This is a highly specific antibody against ApoER2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
848-898/963 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ApoER2 |
| Gene ID Number: |
7804 |
| Swiss Prot: |
Q14114 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature, Binds the endoplasmic reticulum resident receptor-associated protein (RAP), Highly expressed in the initial segment of the epididymis, LRP8 has higher affinity for Reelin than VLDLR, LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development, LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, May also function as an endocytic receptor, Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons, by binding to DAB1 on its cytoplasmic tail, two proteins required for sperm maturation, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
APOER2 MCI1 LRP-8 HSZ75190 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ApoER2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
ApoER2 |
| Short name: |
ApoER2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, ApoER2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6700 |
| Gene: |
LRP8 |
More about : LRP8 |
| Long gene name: |
LDL receptor related protein 8 |
| Synonyms gene name: |
apolipoprotein e receptor , low density lipoprotein receptor-related protein 8 |
| Locus: |
1p32, 3 |
| Discovery year: |
1998-08-13 |
| GenBank acession: |
D50678 |
| Entrez gene record: |
7804 |
| Pubmed identfication: |
8626535 9079678 |
| RefSeq identity: |
NM_004631 |
| Classification: |
Low density lipoprotein receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000008924 |