| Long name: |
FITC Conjugated, UHRF1/2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
UHRF1/2 |
| Specificity: |
This is a highly specific antibody against UHRF1/2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
720-770/793 |
| Subcellular location: |
Helical |
| Source: |
KLH conjugated synthetic peptide derived from human UHRF1 |
| Gene ID number: |
29128, 115426 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also ubiquitinates PCNP leading to its degradation by the proteasome, Binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, CCND1 and CCNE1, E3 SUMO-, Important for G1/S transition, May be involved in DNA repair and chromosomal stability, May participate in methylation-dependent transcriptional regulation, Overexpressed in breast cancer, Through cooperative DNA and histone binding, UHRF2 is an E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network, Ubiquitinates cyclins, and activates TOP2A expression, bone marrow, but not ubiquitin-, in an apparently phosphorylation-independent manner and induces G1 arrest, lung and heart, may contribute to a tighter epigenetic control of gene expression in differentiated cells, protein ligase for ZNF131, testis, Putative E3 ubiquitin-protein ligase, Tissue specificity:Expressed in thymus |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
ICBP90 Np95 FLJ21925 RNF106 TDRD22 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
UHRF1/2 Conjugated |
| Short name: |
FITC Conjugated, UHRF1/2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, UHRF1/2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12556 |
| Gene: |
UHRF1 |
More about : UHRF1 |
| Long gene name: |
ubiquitin like with PHD and ring finger domains 1 |
| Locus: |
19p13, 3 |
| Discovery year: |
2000-03-15 |
| GenBank acession: |
AF129507 |
| Entrez gene record: |
29128 |
| Pubmed identfication: |
10646863 |
| RefSeq identity: |
NM_001048201 |
| Classification: |
PHD finger proteins Ring finger proteins Tudor domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180251 |