| Long name: |
Cy5, 5 Conjugated, UHRF1/2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
UHRF1/2 |
| Specificity: |
This is a highly specific antibody against UHRF1/2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
720-770/793 |
| Subcellular location: |
Helical |
| Source: |
KLH conjugated synthetic peptide derived from human UHRF1 |
| Gene ID number: |
29128, 115426 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also ubiquitinates PCNP leading to its degradation by the proteasome, Binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, CCND1 and CCNE1, E3 SUMO-, Important for G1/S transition, May be involved in DNA repair and chromosomal stability, May participate in methylation-dependent transcriptional regulation, Overexpressed in breast cancer, Through cooperative DNA and histone binding, UHRF2 is an E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network, Ubiquitinates cyclins, and activates TOP2A expression, bone marrow, but not ubiquitin-, in an apparently phosphorylation-independent manner and induces G1 arrest, lung and heart, may contribute to a tighter epigenetic control of gene expression in differentiated cells, protein ligase for ZNF131, testis, Putative E3 ubiquitin-protein ligase, Tissue specificity:Expressed in thymus |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
ICBP90 Np95 FLJ21925 RNF106 TDRD22 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
UHRF1/2 Conjugated |
| Short name: |
Conjugated, UHRF1/2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, UHRF1/2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12556 |
| Gene: |
UHRF1 |
More about : UHRF1 |
| Long gene name: |
ubiquitin like with PHD and ring finger domains 1 |
| Locus: |
19p13, 3 |
| Discovery year: |
2000-03-15 |
| GenBank acession: |
AF129507 |
| Entrez gene record: |
29128 |
| Pubmed identfication: |
10646863 |
| RefSeq identity: |
NM_001048201 |
| Classification: |
PHD finger proteins Ring finger proteins Tudor domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180251 |