| Long name: |
ALEXA FLUOR 488 Conjugated, TMPRSS2 Polyclonal Antibody |
| Also known as: |
Anti-TMPRSS2 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TMPRSS2 |
| Specificity: |
This is a highly specific antibody against TMPRSS2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
320-370/492 |
| Subcellular location: |
Secreted, Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TMPRSS2 |
| Gene ID Number: |
7113 |
| Swiss Prot: |
O15393 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
2, 3, 4a and 4b viruses (HPIV), Essential for spread and pathogenesis of influenza A virus (strains H1N1, Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, H3N2 and H7N9), Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV), and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry, human metapneumovirus (HMPV), human parainfluenza 1, involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity, proteolytic cleavage of ACE2, spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence, which might promote viral uptake, Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
PRSS10 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TMPRSS2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
TMPRSS2 |
| Short name: |
TMPRSS2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, TMPRSS2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11876 |
| Gene: |
TMPRSS2 |
More about : TMPRSS2 |
| Long gene name: |
serine 2 , transmembrane protease |
| Locus: |
21q22, 3 |
| Discovery year: |
1997-05-09 |
| GenBank acession: |
U75329 |
| Pubmed identfication: |
9325052 |
| Classification: |
Proteases, serine |
| Havana BLAST/BLAT: |
OTTHUMG00000086762 |