| Long name: |
Biotin Conjugated, TMPRSS2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TMPRSS2 |
| Specificity: |
This is a highly specific antibody against TMPRSS2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
320-370/492 |
| Subcellular location: |
Secreted, Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human TMPRSS2 |
| Gene ID number: |
7113 |
| Swiss Prot: |
O15393 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
2, 3, 4a and 4b viruses (HPIV), Essential for spread and pathogenesis of influenza A virus (strains H1N1, Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, H3N2 and H7N9), Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV), and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry, human metapneumovirus (HMPV), human parainfluenza 1, involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity, proteolytic cleavage of ACE2, spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence, which might promote viral uptake, Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PRSS10 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TMPRSS2 Conjugated |
| Short name: |
Conjugated, TMPRSS2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, TMPRSS2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11876 |
| Gene: |
TMPRSS2 |
More about : TMPRSS2 |
| Long gene name: |
serine 2 , transmembrane protease |
| Locus: |
21q22, 3 |
| Discovery year: |
1997-05-09 |
| GenBank acession: |
U75329 |
| Pubmed identfication: |
9325052 |
| Classification: |
Proteases, serine |
| Havana BLAST/BLAT: |
OTTHUMG00000086762 |