| Long name: |
TMPRSS2 Primary Polyclonal Antibody |
| Also known as: |
TMPRSS2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TMPRSS2 |
| Specificity: |
This is a highly specific antibody against TMPRSS2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
320-370/492 |
| Subcellular location: |
Secreted, Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TMPRSS2 |
| Gene ID number: |
7113 |
| Swiss Prot: |
O15393 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
2, 3, 4a and 4b viruses (HPIV), Essential for spread and pathogenesis of influenza A virus (strains H1N1, Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, H3N2 and H7N9), Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV), and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry, human metapneumovirus (HMPV), human parainfluenza 1, involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity, proteolytic cleavage of ACE2, spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence, which might promote viral uptake, Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
PRSS10, Serine protease 10, TMPRSS2, Transmembrane protease serine 2, PP9284 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TMPRSS2 |
| Short name: |
TMPRSS2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TMPRSS2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11876 |
| Gene: |
TMPRSS2 |
More about : TMPRSS2 |
| Long gene name: |
serine 2 , transmembrane protease |
| Synonyms: |
PRSS10 |
| Locus: |
21q22, 3 |
| Discovery year: |
1997-05-09 |
| GenBank acession: |
U75329 |
| Pubmed identfication: |
9325052 |
| Classification: |
Proteases, serine |
| Havana BLAST/BLAT: |
OTTHUMG00000086762 |