| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TMPRSS2 |
| Specificity: |
This antibody reacts specifically with TMPRSS2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted, Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TMPRSS2 |
| Gene ID: |
7113 |
| Swiss Prot: |
O15393 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
2, 3, 4a and 4b viruses (HPIV), Essential for spread and pathogenesis of influenza A virus (strains H1N1, Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, H3N2 and H7N9), Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV), and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry, human metapneumovirus (HMPV), human parainfluenza 1, involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity, proteolytic cleavage of ACE2, spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence, which might promote viral uptake, Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PRSS10 |
| Also known as: |
TMPRSS2 Polyclonal Antibody |
| Other name: |
Anti-TMPRSS2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TMPRSS2 |
| Short name: |
Anti-TMPRSS2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TMPRSS2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11876 |
| Gene: |
TMPRSS2 |
More about : TMPRSS2 |
| Long gene name: |
serine 2 , transmembrane protease |
| Locus: |
21q22, 3 |
| Discovery year: |
1997-05-09 |
| GenBank acession: |
U75329 |
| Pubmed identfication: |
9325052 |
| Classification: |
Proteases, serine |
| Havana BLAST/BLAT: |
OTTHUMG00000086762 |