| Long name: |
FITC Conjugated, MCK10 (Tyr513) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MCK10 Tyr513 |
| Specificity: |
This is a highly specific antibody against MCK10 Tyr513 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr513 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human MCK10 around the phosphorylation site of Tyr513 |
| Gene ID number: |
780 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Alternative splicing of this gene results in multiple transcript variants, In addition, In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, Its autophosphorylation is achieved by all collagens so far tested (type I to type VI), The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen, These molecules are involved in the regulation of cell growth, This gene is located on chromosome 6p21, This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain, and brain, and pediatric brain, differentiation and metabolism, esophageal, gastrointestinal tract, lung, ovarian, particularly in the kidney, this protein is significantly over-expressed in several human tumors from breast, 3 in proximity to several HLA class I genes, Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CAK, CD167, CD167a, Cell adhesion kinase, DDR, DDR 1, DDR1, DDR1CD 167, DDR1_HUMAN, Discoidin domain receptor, Discoidin receptor tyrosine kinase isoform a, EDDR 1, Epithelial discoidin domain receptor 1, Epithelial specic receptor kinase, Mammarian carcinoma kinase 10, NTRK 4, Neuroepithelial tyrosine kinase, Neurotrophic tyrosine kinase receptor type 4, PTK 3, PTK 3A protein tyrosine kinase 3A, RTK 6, Receptor tyrosine kinase NEP, TRK E, Tyrosine kinase receptor E, p-MCK10 phospho Y513, MCK10 phospho Y513 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MCK10 (Tyr513) Conjugated |
| Short name: |
FITC Conjugated, MCK10 (Tyr513) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, MCK10 (Tyr513) (Antibody to) |
| Alternative technique: |
antibodies |