| Catalog number: | bs-6258R |
|---|---|
| Price: | 348 € |
| Supplier: | MBS Polyclonals |
| Product name: | Bcr (Tyr360) Antibody |
| Quantity: | 0.12 ml |
| Related search: |
| Long name: | Bcr (Tyr360) Primary Polyclonal Antibody |
|---|---|
| Also known as: | Bcr (Tyr360) PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | Bcr Tyr360 |
| Specificity: | This is a highly specific antibody against Bcr Tyr360 |
| Modification(s): | Phosphorylation |
| Modification site(s): | Tyr360 |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic phosphopeptide derived from human Bcr around the phosphorylation site of Tyr360 [TT(p-Y)RM] |
| Gene ID number: | 613 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | Although the BCR-ABL fusion protein has been extensively studied, The chromosome 22 breakpoint for this translocation is located within the BCR gene, The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac, The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, Two transcript variants encoding different isoforms have been found for this gene, the function of the normal BCR gene product is not clear, the gene at the chromosome 9 breakpoint, which is often found in patients with chronic myelogenous leukemia, A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | ALL, BCR 1, BCR/ABL FUSION GENE INCLUDED, BCR/FGFR1 FUSION GENE INCLUDED, BCR/PDGFRA FUSION GENE INCLUDED, BCR1, BCR_HUMAN, Bcrphospho Y360, CML, P-Bcrphospho Y360, PHL, breakpoint cluster region, Bcr phospho Y360 |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | Bcr (Tyr360) |
| Short name: | Bcr (Tyr360) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | Bcr (Tyr360) (Antibody to) |
| Alternative technique: | antibodies |
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