| Long name: |
FITC Conjugated, Estrogen Related Receptor gamma Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Estrogen Related Receptor gamma |
| Specificity: |
This is a highly specific antibody against Estrogen Related Receptor gamma |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ESRRG/Estrogen Related Receptor gamma |
| Gene ID number: |
2104 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
All members of the ESRR family share an almost identical DNA binding domain, It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, Multiple alternatively spliced transcript variants have been identified, The ESRR family is closely related to the estrogen receptor (ER) family, The ESRR members are orphan nuclear receptors, They share target genes, and activate genes controlled by both response elements in the absence of any ligands, and by targeting the same set of genes, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation, co-regulators and promoters, modulates cell proliferation and estrogen signaling in breast cancer, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways, they bind to the estrogen response element and steroidogenic factor 1 response element, which belongs to the nuclear hormone receptor superfamily, which is composed of two C4-type zinc finger motifs, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region, This gene encodes a member of the estrogen receptor-related receptor (ESRR) family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
ERR G2, ERR gamma 2, ERR gamma-2, ERR3, ERR3_HUMAN, ERRG 2, ERRG2, ESRRG, Estrogen receptor related protein 3, Estrogen receptor-related protein 3, Estrogen-related receptor gamma, NR3B3, Nuclear receptor subfamily 3 group B member 3, ERR 3 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Estrogen Related Receptor gamma Conjugated |
| Short name: |
FITC Conjugated, Estrogen Receptor gamma Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Estrogen Related Receptor g (Antibody to) |
| Alternative technique: |
antibodies |