| Long name: |
ALEXA FLUOR 488 Conjugated, Estrogen Related Receptor gamma Antibody |
| Also known as: |
Anti-Estrogen Related Receptor gamma PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Estrogen Related Receptor gamma |
| Specificity: |
This is a highly specific antibody against Estrogen Related Receptor gamma |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ESRRG/Estrogen Related Receptor gamma |
| Gene ID Number: |
2104 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
All members of the ESRR family share an almost identical DNA binding domain, It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, Multiple alternatively spliced transcript variants have been identified, The ESRR family is closely related to the estrogen receptor (ER) family, The ESRR members are orphan nuclear receptors, They share target genes, and activate genes controlled by both response elements in the absence of any ligands, and by targeting the same set of genes, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation, co-regulators and promoters, modulates cell proliferation and estrogen signaling in breast cancer, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways, they bind to the estrogen response element and steroidogenic factor 1 response element, which belongs to the nuclear hormone receptor superfamily, which is composed of two C4-type zinc finger motifs, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region, This gene encodes a member of the estrogen receptor-related receptor (ESRR) family |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
NR3B3 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Estrogen Receptor gamma Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Estrogen Related Receptor gamma |
| Short name: |
Estrogen Receptor gamma Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Estrogen Related Receptor g (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3474 |
| Gene: |
ESRRG |
More about : ESRRG |
| Long gene name: |
estrogen related receptor gamma |
| Locus: |
1q41 |
| Discovery year: |
1998-02-17 |
| GenBank acession: |
AF058291 |
| Entrez gene record: |
2104 |
| Pubmed identfication: |
9676434 10072763 |
| RefSeq identity: |
NM_206595 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000037025 |