| Long name: |
DIRAS1 Primary Polyclonal Antibody |
| Also known as: |
DIRAS1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DIRAS1 |
| Specificity: |
This is a highly specific antibody against DIRAS1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DIRAS1 |
| Gene ID number: |
148252 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It is highly expressed in heart and brain, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing), Ras and ras-related proteins are often deregulated in cancers, Ras proteins function as binary molecular switches that control intracellular signaling networks, Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, and cell migration, and decreased apoptosis, apoptosis, cell adhesion, designated H-Ras, differentiation, leading to increased invasion and metastasis, proliferation, DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form, The three human RAS genes encode highly related 188 to 189 amino acid proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DIRAS family GTP binding RAS like 1, Distinct subgroup of the Ras family member 1, GBTS1, GTP binding protein Di Ras1, RIG, Ras related inhibitor of cell growth, Rig protein, Small GTP binding tumor suppressor 1, Di Ras1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DIRAS1 |
| Short name: |
DIRAS1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DIRAS1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19127 |
| Gene: |
DIRAS1 |
More about : DIRAS1 |
| Long gene name: |
DIRAS family GTPase 1 |
| Synonyms gene name: |
DIRAS family, GTP-binding RAS-like 1 |
| Synonyms: |
Di-Ras1 GBTS1 RIG |
| Locus: |
19p13, 3 |
| Discovery year: |
2003-02-07 |
| GenBank acession: |
BC030660 |
| Entrez gene record: |
148252 |
| Pubmed identfication: |
12107278 |
| Classification: |
RAS type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000180439 |