| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DIRAS1 |
| Specificity: |
This antibody reacts specifically with DIRAS1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DIRAS1 |
| Gene ID: |
148252 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is highly expressed in heart and brain, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing), Ras and ras-related proteins are often deregulated in cancers, Ras proteins function as binary molecular switches that control intracellular signaling networks, Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, and cell migration, and decreased apoptosis, apoptosis, cell adhesion, designated H-Ras, differentiation, leading to increased invasion and metastasis, proliferation, DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form, The three human RAS genes encode highly related 188 to 189 amino acid proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Di-Ras1 GBTS1 RIG |
| Also known as: |
DIRAS1 Polyclonal Antibody |
| Other name: |
Anti-DIRAS1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DIRAS1 |
| Short name: |
Anti-DIRAS1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DIRAS1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
19127 |
| Gene: |
DIRAS1 |
More about : DIRAS1 |
| Long gene name: |
DIRAS family GTPase 1 |
| Synonyms gene name: |
DIRAS family, GTP-binding RAS-like 1 |
| Locus: |
19p13, 3 |
| Discovery year: |
2003-02-07 |
| GenBank acession: |
BC030660 |
| Entrez gene record: |
148252 |
| Pubmed identfication: |
12107278 |
| Classification: |
RAS type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000180439 |