| Long name: |
FITC Conjugated, DIRAS1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DIRAS1 |
| Specificity: |
This is a highly specific antibody against DIRAS1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DIRAS1 |
| Gene ID number: |
148252 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It is highly expressed in heart and brain, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing), Ras and ras-related proteins are often deregulated in cancers, Ras proteins function as binary molecular switches that control intracellular signaling networks, Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, and cell migration, and decreased apoptosis, apoptosis, cell adhesion, designated H-Ras, differentiation, leading to increased invasion and metastasis, proliferation, DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form, The three human RAS genes encode highly related 188 to 189 amino acid proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
Di-Ras1 GBTS1 RIG |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DIRAS1 Conjugated |
| Short name: |
FITC Conjugated, DIRAS1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, DIRAS1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19127 |
| Gene: |
DIRAS1 |
More about : DIRAS1 |
| Long gene name: |
DIRAS family GTPase 1 |
| Synonyms gene name: |
DIRAS family, GTP-binding RAS-like 1 |
| Locus: |
19p13, 3 |
| Discovery year: |
2003-02-07 |
| GenBank acession: |
BC030660 |
| Entrez gene record: |
148252 |
| Pubmed identfication: |
12107278 |
| Classification: |
RAS type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000180439 |