| Long name: |
RbAp48 Primary Polyclonal Antibody |
| Also known as: |
RbAp48 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RbAp48 |
| Specificity: |
This is a highly specific antibody against RbAp48 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RbAp48 |
| Gene ID number: |
5928 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It is also a component of the DREAM complex, RpAp48 also interacts with the retinoblastoma protein, These complexes include Chromatin Assembly Factor 1 (CAF1), and histone deacetylation, and the PRC2 complex, and with SPEN/MINT and BRCA1, chromatin remodeling, the core histone deacetylase (HDAC) complex, the nucleosome remodeling and histone deacetylation complex NuRD, the nucleosome remodeling factor (NURF) complex, which is required for chromatin assembly following DNA replication and repair, which promotes histone deacetylation and subsequent transcriptional repression, which promotes repression of homeotic genes during development, which represses cell cycle-dependent genes in quiescent cells, RbAp48 (Retinoblastoma-binding protein p48 or Rb-associated protein p48)is a WD repeat protein that is a core histone binding subunit common to several complexes involved in chromatin assembly |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CAF-1 subunit C, CAF-I 48 kDa subunit, CAF-I p48, Chromatin assembly factor 1 subunit C, Chromatin assembly factor I p48 subunit, Histone-binding protein RBBP4, Nucleosome-remodeling factor subunit RBAP48, RBBP-4, Retinoblastoma-binding protein 4, Retinoblastoma-binding protein p48, RBBP4_HUMAN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RbAp48 |
| Short name: |
RbAp48 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RbAp48 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9887 |
| Gene: |
RBBP4 |
More about : RBBP4 |
| Long gene name: |
RB binding protein 4, chromatin remodeling factor |
| Synonyms gene name: |
retinoblastoma-binding protein 4 retinoblastoma binding protein 4 |
| Synonyms: |
RbAp48 NURF55 lin-53 |
| Locus: |
1p35, 1 |
| Discovery year: |
1995-05-05 |
| GenBank acession: |
BC053904 |
| Entrez gene record: |
5928 |
| Pubmed identfication: |
8350924 14609955 17531812 |
| RefSeq identity: |
NM_005610 |
| Classification: |
NuRD complex Polycomb repressive complex 2 EMSY complex SIN3 histone deacetylase complex WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000007998 |