NARC1 Antibody, Cy5 Conjugated

Catalog number:	bs-6060R-Cy5 Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	NARC1 Antibody, Cy5 Conjugated
Quantity:	0.1ml
Related search:	antibody narc antibodies pubmed receptor ldlr convertase short

More details Need more?:

Long name:	Cy5 Conjugated, NARC1 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	5, Cy5
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	NARC1
Specificity:	This is a highly specific antibody against NARC1
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	235-285/692
Subcellular location:	Lysosome, Secreted, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human PCSK9/NARC1
Gene ID number:	255738
Swiss Prot:	Q8NBP7
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway, Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), Can induce ubiquitination of LDLR leading to its subsequent degradation (PubMed:18799458, Inhibits epithelial Na(+) channel (ENaC)-mediated Na(+) absorption by reducing ENaC surface expression primarily by increasing its proteasomal degradation, Inhibits intracellular degradation of APOB via the autophagosome/lysosome pathway in a LDLR-independent manner, Involved in the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway (PubMed:18660751), May prevent the recycling of LDLR from endosomes to the cell surface or direct it to lysosomes for degradation, PubMed:17461796, PubMed:18197702, PubMed:22074827), Regulates neuronal apoptosis via modulation of LRP8/APOER2 levels and related anti-apoptotic signaling pathways, and promotes their degradation in intracellular acidic compartments (PubMed:18039658), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), very low density lipoprotein receptor (VLDLR), Crucial player in the regulation of plasma cholesterol homeostasis
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	625, 650nm/670nm
Synonyms:	HCHOLA3, LDLCQ1, NARC-1, NARC1, Neural apoptosis-regulated convertase 1, PC9, PCSK9, PSEC0052, Proprotein convertase 9, Proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9, FH3
Properties:	Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	NARC1 Conjugated
Short name:	Conjugated, NARC1 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy5
Alternative name:	cyanine 5 coupled, NARC1 (Antibody to)
Alternative technique:	antibodies

• #antibody
• #narc
• #antibodies
• #pubmed
• #receptor
• #ldlr
• #convertase
• #short