| Long name: |
FITC Conjugated, TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) |
| Specificity: |
This is a highly specific antibody against TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr516 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from rat NTRK2 around the phosphorylation site of Tyr516 |
| Gene ID number: |
4915 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
BDNF and to a lesser extent, By comparison, NGFR p175, NGFR p175 accelerates Trk activation and may recruit downstream dffector molecules to the ligand-bound receptor complex, NT-3, Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk gp 140 in neural cell lines and in embryonic dorsal root ganglia, The prototype member of this gene family, The third member of the Trk receptor family, Trk A, Trk C gp140, Trk C incodes a 140 kDa protein, binds to neurotrophic factors with low affinity but is required for efficient signaling, but not NGF, can induce tyrosine phophorylayion of Trk B gp 145, encodes a 140 kDa cell surface receptor, gp140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3, the expression of which is restricted in vivo to neurons of the sensory spinal and cranial gangliaof neurocrest origin, An additional component of the Trk receptor complex, The Trk family of nerve growth factor receptors includes Trk A(also referfed to as Trk A gp140), Trk B and Trk C |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
BDNF tropomyosine receptor kinase B, BDNF/NT 3 growth factors receptor, BDNF/NT-3 growth factors receptor, Brain derived neurotrophic factor receptor, GP145 TrkB, GP145-TrkB, GP145-TrkB/GP95-TrkB, GP95 TrkB, NTRK 2, NTRK2_HUMAN, Neurotrophic tyrosine kinase receptor type 2, Neurotrophin receptor tyrosine kinase type 2, Ntrk2, Obesity, RATTRKB1, TRKB, TRKB1, Tkrb, Trk B, Trk-B, TrkB, TrkB Tyr515, TrkB tyrosine kinase, Tyrosine Receptor Kinase B, Tyrosine kinase, Tyrosine receptor kinase B, and developmental delay, hyperphagia, included, tyrosine kinase receptor B, Pyk2, TrKC Tyr516 and TrKA 496 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) Conjugated |
| Short name: |
FITC Conjugated, TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TrkA (Tyr496) and TrkB (Tyr516) and TrKC (Tyr516) (Antibody to) |
| Alternative technique: |
antibodies |