| Long name: |
ALEXA FLUOR 488 Conjugated, TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) Antibody |
| Also known as: |
Anti-TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) |
| Specificity: |
This is a highly specific antibody against TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) |
| Modification: |
Phosphorylation |
| Modification Site: |
Tyr516 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from rat NTRK2 around the phosphorylation site of Tyr516 |
| Gene ID Number: |
4915 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
BDNF and to a lesser extent, By comparison, NGFR p175, NGFR p175 accelerates Trk activation and may recruit downstream dffector molecules to the ligand-bound receptor complex, NT-3, Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk gp 140 in neural cell lines and in embryonic dorsal root ganglia, The prototype member of this gene family, The third member of the Trk receptor family, Trk A, Trk C gp140, Trk C incodes a 140 kDa protein, binds to neurotrophic factors with low affinity but is required for efficient signaling, but not NGF, can induce tyrosine phophorylayion of Trk B gp 145, encodes a 140 kDa cell surface receptor, gp140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3, the expression of which is restricted in vivo to neurons of the sensory spinal and cranial gangliaof neurocrest origin, An additional component of the Trk receptor complex, The Trk family of nerve growth factor receptors includes Trk A(also referfed to as Trk A gp140), Trk B and Trk C |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
BDNF tropomyosine receptor kinase B, BDNF/NT 3 growth factors receptor, BDNF/NT-3 growth factors receptor, Brain derived neurotrophic factor receptor, GP145 TrkB, GP145-TrkB, GP145-TrkB/GP95-TrkB, GP95 TrkB, NTRK 2, NTRK2_HUMAN, Neurotrophic tyrosine kinase receptor type 2, Neurotrophin receptor tyrosine kinase type 2, Ntrk2, Obesity, RATTRKB1, TRKB, TRKB1, Tkrb, Trk B, Trk-B, TrkB, TrkB Tyr515, TrkB tyrosine kinase, Tyrosine Receptor Kinase B, Tyrosine kinase, Tyrosine receptor kinase B, and developmental delay, hyperphagia, included, tyrosine kinase receptor B, Pyk2, TrKC Tyr516 and TrKA 496 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) |
| Short name: |
TrkA (Tyr496) + TrkB (Tyr516) + TrKC (Tyr516) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, TrkA (Tyr496) and TrkB (Tyr516) and TrKC (Tyr516) (Antibody to) |
| Alternative technique: |
antibodies |