| Long name: |
FITC Conjugated, PMVK Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PMVK |
| Specificity: |
This is a highly specific antibody against PMVK |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1-50/192 |
| Subcellular location: |
Intracellular |
| Source: |
KLH conjugated synthetic peptide derived from human PMVK |
| Gene ID number: |
10654 |
| Swiss Prot: |
Q15126 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Induced by sterol, PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway, PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway, and pancreas with lower expression in brain, kidney, liver, placenta and lung, skeletal muscle, which houses over 3, 000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome, PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
PMK PMKA HUMPMKI |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PMVK Conjugated |
| Short name: |
FITC Conjugated, PMVK Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, PMVK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9141 |
| Gene: |
PMVK |
More about : PMVK |
| Long gene name: |
phosphomevalonate kinase |
| Locus: |
1q21, 3 |
| Discovery year: |
1999-07-09 |
| GenBank acession: |
L77213 |
| Entrez gene record: |
10654 |
| Pubmed identfication: |
8663599 10191291 |
| RefSeq identity: |
NM_006556 |
| Havana BLAST/BLAT: |
OTTHUMG00000037415 |