| Long name: |
ALEXA FLUOR 488 Conjugated, PMVK Polyclonal Antibody |
| Also known as: |
Anti-PMVK PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PMVK |
| Specificity: |
This is a highly specific antibody against PMVK |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-50/192 |
| Subcellular location: |
Intracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PMVK |
| Gene ID Number: |
10654 |
| Swiss Prot: |
Q15126 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Induced by sterol, PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway, PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway, and pancreas with lower expression in brain, kidney, liver, placenta and lung, skeletal muscle, which houses over 3, 000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome, PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
PMK PMKA HUMPMKI |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PMVK Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
PMVK |
| Short name: |
PMVK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, PMVK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9141 |
| Gene: |
PMVK |
More about : PMVK |
| Long gene name: |
phosphomevalonate kinase |
| Locus: |
1q21, 3 |
| Discovery year: |
1999-07-09 |
| GenBank acession: |
L77213 |
| Entrez gene record: |
10654 |
| Pubmed identfication: |
8663599 10191291 |
| RefSeq identity: |
NM_006556 |
| Havana BLAST/BLAT: |
OTTHUMG00000037415 |