ATF4/CREB-2 Antibody, Biotin Conjugated

Catalog number:	bs-1531R-Biotin Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	ATF4/CREB-2 Antibody, Biotin Conjugated
Quantity:	0.1ml
Related search:	antibody gene atfcreb transcription synonyms enhancer

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Long name:	Biotin Conjugated, ATF4/CREB-2 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	ATF4/CREB-2
Specificity:	This is a highly specific antibody against ATF4/CREB-2
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	240-290/351
Subcellular location:	Cell membrane, Nucleus, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human ATF4
Gene ID number:	468
Swiss Prot:	P18848
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Activates transcription of SIRT4, Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes, Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity), In concert with DDIT3/CHOP, It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I, Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4, Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress, a sequence present in many viral and cellular promoters, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA, Transcriptional activator
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	TAXREB67 CREB-2
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	ATF4/CREB-2 Conjugated
Short name:	Conjugated, ATF4/CREB-2 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, ATF4/CREB-2 (Antibody to)
Alternative technique:	antibodies
Identity:	786
Gene:	ATF4 | More about : ATF4
Long gene name:	activating transcription factor 4
Synonyms gene:	TXREB
Synonyms gene name:	activating transcription factor 4 (tax-responsive enhancer element B67)
Synonyms name:	tax-responsive enhancer element B67
Locus:	22q13, 1
Discovery year:	1992-06-09
GenBank acession:	D90209
Entrez gene record:	468
Pubmed identfication:	1847461 1534408
RefSeq identity:	NM_001675
Classification:	Basic leucine zipper proteins
Havana BLAST/BLAT:	OTTHUMG00000151099

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• #enhancer