| Long name: |
Fast skeletal Myosin Primary Polyclonal Antibody |
| Also known as: |
Fast skeletal Myosin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Fast skeletal Myosin |
| Specificity: |
This antibody may recognize myosin light chain 5, myosin light chain 7, or myosin regulatory light chain 10, This is a highly specific antibody against Fast skeletal Myosin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
120-170/170 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MRLC2 |
| Gene ID number: |
29895 |
| Swiss Prot: |
Q96A32 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of Myosin light chain (MLC) by Myosin light chain kinase, Conventional Myosins are hexameric proteins consisting of two heavy chain subunits, Myosin heavy chains, Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the speed of contraction of skeletal muscle, Three general classes of Myosin have been cloned: smooth muscle Myosins, Various isoforms of myosin heavy chains are differentially expressed depending on the functional activity of the muscle, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits, contain Actin-activated ATPase activity which generates the motor function of Myosin, striated muscle Myosins and non-muscle Myosins , ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements, which are encoded by the MYH gene family, Myosin is a highly conserved |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Fast skeletal myosin light chain 2, HUMMLC2B, MLC2B, MYL11, MYLPF, Myosin regulatory light chain 2, skeletal muscle isoform, MRLC2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Fast skeletal Myosin |
| Short name: |
Fast skeletal Myosin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Fast skeletal Myosin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29824 |
| Gene: |
MYLPF |
More about : MYLPF |
| Long gene name: |
fast skeletal muscle , myosin light chain, phosphorylatable |
| Synonyms: |
MRLC2 HUMMLC2B MYL11 |
| Synonyms name: |
light chain 11, myosin, regulatory myosin regulatory light chain 2 |
| Locus: |
16p11, 2 |
| Discovery year: |
2009-03-06 |
| GenBank acession: |
AF363061 |
| Entrez gene record: |
29895 |
| Pubmed identfication: |
6179945 |
| RefSeq identity: |
NM_013292 |
| Classification: |
Myosin light chains EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132399 |