| Long name: |
FITC Conjugated, Chondroitin sulfate proteoglycan NG2 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Chondroitin sulfate proteoglycan NG2 |
| Specificity: |
This is a highly specific antibody against Chondroitin sulfate proteoglycan NG2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
730-780/2322 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human Chondroitin sulfate proteoglycan NG2 |
| Gene ID number: |
1464 |
| Swiss Prot: |
Q6UVK1 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ACK1 and BCAR1, Binds through its extracellular N-terminus growth factors, Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate, Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins, May activate FAK and ERK1/ERK2 signaling cascades, May also inhibit neurite outgrowth and growth cone collapse during axon regeneration, May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin, May promote retraction fiber formation and cell polarization through Rho GTPase activation, May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties, May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, extracellular matrix proteases modulating their activity, Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
NG2 G16 RING5 RMA1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Chondroitin sulfate proteoglycan NG2 Conjugated |
| Short name: |
FITC Conjugated, Chondroitin sulfate proteoglycan NG2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Chondroitin sulfate proteoglycan NG2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10068 |
| Gene: |
RNF5 |
More about : RNF5 |
| Long gene name: |
ring finger protein 5 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , ring finger protein 5 |
| Locus: |
6p21, 32 |
| Discovery year: |
1997-10-16 |
| GenBank acession: |
U89336 |
| Entrez gene record: |
6048 |
| Pubmed identfication: |
9533025 |
| RefSeq identity: |
NM_006913 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000031093 |