| Long name: |
Chondroitin sulfate proteoglycan NG2 Antibody |
| Also known as: |
Chondroitin sulfate proteoglycan NG2 Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Chondroitin sulfate proteoglycan NG2 |
| Specificity: |
This is a highly specific antibody against Chondroitin sulfate proteoglycan NG2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
730-780/2322 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Chondroitin sulfate proteoglycan NG2 |
| Gene ID number: |
1464 |
| Swiss Prot: |
Q6UVK1 |
| Tested Applications: |
IF(IHC-P), IHC-P, FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), FCM(1:20-100) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ACK1 and BCAR1, Binds through its extracellular N-terminus growth factors, Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate, Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins, May activate FAK and ERK1/ERK2 signaling cascades, May also inhibit neurite outgrowth and growth cone collapse during axon regeneration, May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin, May promote retraction fiber formation and cell polarization through Rho GTPase activation, May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties, May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, extracellular matrix proteases modulating their activity, Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CSPG4, Chondroitin sulfate proteoglycan 4, Chondroitin sulfate proteoglycan NG2, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, Melanoma chondroitin sulfate proteoglycan, Melanoma-associated chondroitin sulfate proteoglycan, NG2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Chondroitin sulfate proteoglycan NG2 |
| Short name: |
Chondroitin sulfate proteoglycan NG2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Chondroitin sulfate proteoglycan NG2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10068 |
| Gene: |
RNF5 |
More about : RNF5 |
| Long gene name: |
ring finger protein 5 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , ring finger protein 5 |
| Synonyms: |
NG2 G16 RING5 RMA1 |
| Locus: |
6p21, 32 |
| Discovery year: |
1997-10-16 |
| GenBank acession: |
U89336 |
| Entrez gene record: |
6048 |
| Pubmed identfication: |
9533025 |
| RefSeq identity: |
NM_006913 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000031093 |