| Long name: |
Cy3 Conjugated, MAP 1A/1B LC3 A/B Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MAP 1A/1B LC3 Alpha/Beta |
| Specificity: |
This is a highly specific antibody against MAP 1A/1B LC3 Alpha/Beta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
20-70/121 |
| Subcellular location: |
Cell membrane, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human MAP LC3 Alpha |
| Gene ID number: |
54901, 84557 |
| Swiss Prot: |
Q9GZQ8, Q9H492 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It is expressed primarily in heart, LC3 enhances fibronectin mRNA translation in ductus arteriosus cells through association with 60S ribosomes and binding to an AU-rich element in the 3â, LC3-I is formed by the removal of the C-terminal 22 amino acids from newly synthesized LC3â, MAP LC3 Beta may also be involved in formation of autophagosomal vacuoles, MAP-LC3M Beta, MAP-light chain 3 beta (MAP-LC3 Beta) and MAP-light chain 3 alpha (MAP-LC3 alpha) are subunits of both MAP1A and MAP1B, This facilitates sorting of fibronectin mRNA onto rough endoplasmic reticulum and translation, Two forms of LC3 Beta, a homolog of Apg8p, are produced post-translationally, brain and skeletal muscle, followed by the conversion of a fraction of LC3-I into LC3-II, is essential for autophagy and associated to the autophagosome membranes after processing, testis, the cytosolic LC3-I and the membrane-bound LC3-II, untranslated region of fibronectin mRNA, &circ, &euro, «, &trade, Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and in maintaining the balance between neuronal plasticity and rigidity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
MAP1BLC3 MAP1ALC3 LC3 LC3A ATG8E |
| Properties: |
1 of the MAP 1A/1B LC3 A/B Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MAP 1A/1B LC3 A/B Conjugated |
| Short name: |
Conjugated, MAP 1A/1B LC3 A/B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, mitogen-stimulated protein kinase 1A/1B LC3 A/B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6838 |
| Gene: |
MAP1LC3A |
More about : MAP1LC3A |
| Long gene name: |
microtubule associated protein 1 light chain 3 alpha |
| Locus: |
20q11, 22 |
| Discovery year: |
2000-06-29 |
| Entrez gene record: |
84557 |
| Pubmed identfication: |
8833088 17580304 |
| RefSeq identity: |
NM_181509 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000032306 |