| Long name: |
Cy5, 5 Conjugated, hnRNP K Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
hnRNP K |
| Specificity: |
This is a highly specific antibody against hnRNP K |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
200-250/463 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human hnRNP K |
| Gene ID number: |
3190 |
| Swiss Prot: |
P61978 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
As far as transcription repression is concerned, Binds tenaciously to poly(C) sequences, Can also bind poly(C) single-stranded DNA, Likely to play a role in the nuclear metabolism of hnRNAs, Plays an important role in p53/TP53 response to DNA damage, This interaction is necessary for the induction of apoptosis, When sumoylated, a non-coding RNA induced by p53/TP53, acting at the level of both transcription activation and repression, acts as a transcriptional coactivator of p53/TP53, acts by interacting with long intergenic RNA p21 (lincRNA-p21), but not cell cycle arrest, particularly for pre-mRNAs that contain cytidine-rich sequences, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity), One of the major pre-mRNA-binding proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
HNRNPK, HNRPK, Heterogeneous nuclear ribonucleoprotein K, TUNP, Transformation up-regulated nuclear protein, hnRNP K, CSBP |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
hnRNP K Conjugated |
| Short name: |
Conjugated, hnRNP K Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, hnRNP K (Antibody to) |
| Alternative technique: |
antibodies |