| Long name: |
FITC Conjugated, hnRNP K Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
hnRNP K |
| Specificity: |
This is a highly specific antibody against hnRNP K |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
200-250/463 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human hnRNP K |
| Gene ID number: |
3190 |
| Swiss Prot: |
P61978 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
As far as transcription repression is concerned, Binds tenaciously to poly(C) sequences, Can also bind poly(C) single-stranded DNA, Likely to play a role in the nuclear metabolism of hnRNAs, Plays an important role in p53/TP53 response to DNA damage, This interaction is necessary for the induction of apoptosis, When sumoylated, a non-coding RNA induced by p53/TP53, acting at the level of both transcription activation and repression, acts as a transcriptional coactivator of p53/TP53, acts by interacting with long intergenic RNA p21 (lincRNA-p21), but not cell cycle arrest, particularly for pre-mRNAs that contain cytidine-rich sequences, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity), One of the major pre-mRNA-binding proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
HNRNPK, HNRPK, Heterogeneous nuclear ribonucleoprotein K, TUNP, Transformation up-regulated nuclear protein, hnRNP K, CSBP |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
hnRNP K Conjugated |
| Short name: |
FITC Conjugated, hnRNP K Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, hnRNP K (Antibody to) |
| Alternative technique: |
antibodies |