| Long name: |
Biotin Conjugated, hnRNP K Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
hnRNP K |
| Specificity: |
This is a highly specific antibody against hnRNP K |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
200-250/463 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human hnRNP K |
| Gene ID number: |
3190 |
| Swiss Prot: |
P61978 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
As far as transcription repression is concerned, Binds tenaciously to poly(C) sequences, Can also bind poly(C) single-stranded DNA, Likely to play a role in the nuclear metabolism of hnRNAs, Plays an important role in p53/TP53 response to DNA damage, This interaction is necessary for the induction of apoptosis, When sumoylated, a non-coding RNA induced by p53/TP53, acting at the level of both transcription activation and repression, acts as a transcriptional coactivator of p53/TP53, acts by interacting with long intergenic RNA p21 (lincRNA-p21), but not cell cycle arrest, particularly for pre-mRNAs that contain cytidine-rich sequences, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity), One of the major pre-mRNA-binding proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
HNRNPK, HNRPK, Heterogeneous nuclear ribonucleoprotein K, TUNP, Transformation up-regulated nuclear protein, hnRNP K, CSBP |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
hnRNP K Conjugated |
| Short name: |
Conjugated, hnRNP K Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, hnRNP K (Antibody to) |
| Alternative technique: |
antibodies |