| Long name: |
ALEXA FLUOR 647 Conjugated, Sphingomyelin Synthase 1 Antibody |
| Also known as: |
Anti-Sphingomyelin Synthase 1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Sphingomyelin Synthase 1 |
| Specificity: |
This is a highly specific antibody against Sphingomyelin Synthase 1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
50-100/419 |
| Subcellular location: |
Intracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Sphingomyelin Synthase 1 |
| Gene ID Number: |
259230 |
| Swiss Prot: |
Q86VZ5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, Major form in macrophages, May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide, Required for cell growth in certain cell types such as HeLa cells, Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide, elevated temperature and exogenously supplied sphingolipids, on to the primary hydroxyl of ceramide, osmotic stress, phosphatidylcholine, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate, sphingomyelin, through transfer of the phosphatidyl head group, Sphingomyelin synthases synthesize the sphingolipid |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
MOB MGC17342 SMS1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Sphingomyelin Synthase 1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Sphingomyelin Synthase 1 |
| Short name: |
Sphingomyelin Synthase 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Sphingomyelin Synthase 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29799 |
| Gene: |
SGMS1 |
More about : SGMS1 |
| Long gene name: |
sphingomyelin synthase 1 |
| Synonyms gene: |
TMEM23 |
| Synonyms gene name: |
transmembrane protein 23 |
| Synonyms name: |
phosphatidylcholine:ceramide cholinephosphotransferase 1 |
| Locus: |
10q11, 23 |
| Discovery year: |
2004-03-23 |
| GenBank acession: |
AY280959 |
| Entrez gene record: |
259230 |
| Pubmed identfication: |
11841947 14976195 |
| RefSeq identity: |
NM_147156 |
| Classification: |
Sterile alpha motif domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000018231 |