| Long name: |
Biotin Conjugated, ADAMTS4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ADAMTS4 |
| Specificity: |
Due to the similarity this protein to ADAMTS1, based upon a 73% sequence similarity in the epitope region, there is a chance that this antibody may have a cross-reactivity with this protein, This is a highly specific antibody against ADAMTS4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
530-580/839 |
| Subcellular location: |
Secreted, Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human ADAMTS4 |
| Gene ID number: |
9507 |
| Swiss Prot: |
O75173 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Cleaves aggrecan at the '392-Glu-|-Ala-393' site, Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease, May play an important role in the destruction of aggrecan in arthritic diseases, a cartilage proteoglycan, and may be involved in its turnover, Cleaves aggrecan |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
KIAA0688 ADAMTS-2 ADMP-1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ADAMTS4 Conjugated |
| Short name: |
Conjugated, ADAMTS4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, ADAMTS4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
220 |
| Gene: |
ADAMTS4 |
More about : ADAMTS4 |
| Long gene name: |
ADAM metallopeptidase with thrombospondin type 1 motif 4 |
| Synonyms gene name: |
4 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif |
| Locus: |
1q23, 3 |
| Discovery year: |
1999-04-15 |
| GenBank acession: |
AB014588 |
| Entrez gene record: |
9507 |
| Pubmed identfication: |
10094461 |
| RefSeq identity: |
NM_005099 |
| Classification: |
ADAM metallopeptidases with thrombospondin type 1 motif |
| Havana BLAST/BLAT: |
OTTHUMG00000034349 |