| Long name: |
ADAMTS4 Primary Polyclonal Antibody |
| Also known as: |
ADAMTS4 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ADAMTS4 |
| Specificity: |
Due to the similarity this protein to ADAMTS1, based upon a 73% sequence similarity in the epitope region, there is a chance that this antibody may have a cross-reactivity with this protein, This is a highly specific antibody against ADAMTS4 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
530-580/839 |
| Subcellular location: |
Secreted, Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAMTS4 |
| Gene ID number: |
9507 |
| Swiss Prot: |
O75173 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Cleaves aggrecan at the '392-Glu-|-Ala-393' site, Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease, May play an important role in the destruction of aggrecan in arthritic diseases, a cartilage proteoglycan, and may be involved in its turnover, Cleaves aggrecan |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS 4, ADAM-TS4, ADAMTS-2, ADAMTS-4, ADAMTS4, Aggrecanase-1, KIAA0688, UNQ769/PRO1563, ADMP-1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ADAMTS4 |
| Short name: |
ADAMTS4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ADAMTS4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
220 |
| Gene: |
ADAMTS4 |
More about : ADAMTS4 |
| Long gene name: |
ADAM metallopeptidase with thrombospondin type 1 motif 4 |
| Synonyms gene name: |
4 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif |
| Synonyms: |
KIAA0688 ADAMTS-2 ADMP-1 |
| Locus: |
1q23, 3 |
| Discovery year: |
1999-04-15 |
| GenBank acession: |
AB014588 |
| Entrez gene record: |
9507 |
| Pubmed identfication: |
10094461 |
| RefSeq identity: |
NM_005099 |
| Classification: |
ADAM metallopeptidases with thrombospondin type 1 motif |
| Havana BLAST/BLAT: |
OTTHUMG00000034349 |