| Long name: |
ALEXA FLUOR 488 Conjugated, ZEB Polyclonal Antibody |
| Also known as: |
2 PAb ALEXA FLUOR 488, Anti-Zinc finger E-box-binding homeobox 1 & |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
2, Zinc finger E-box-binding homeobox 1 & |
| Specificity: |
2, This is a highly specific antibody against Zinc finger E-box-binding homeobox 1 & |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
210-260/1124 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZEB1 |
| Gene ID Number: |
6935, 9839 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type, May be responsible for transcriptional repression of the IL-2 gene, Promotes tumorigenicity by repressing stemness-inhibiting microRNAs, Represses BCL6 transcription in the presence of the corepressor CTBP1, Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1, Inhibits interleukin-2 (IL-2) gene expression |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
BZP ZEB AREB6 NIL-2-A Zfhep Zfhx1a FECD6 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ZEB Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
ZEB |
| Short name: |
ZEB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, ZEB (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11642 |
| Gene: |
ZEB1 |
More about : ZEB1 |
| Long gene name: |
zinc finger E-box binding homeobox 1 |
| Synonyms gene: |
TCF8 PPCD3 |
| Synonyms gene name: |
transcription factor 8 (represses interleukin 2 expression) posterior polymorphous corneal dystrophy 3 |
| Locus: |
10p11, 22 |
| Discovery year: |
1991-12-17 |
| GenBank acession: |
AK091478 |
| Entrez gene record: |
6935 |
| Pubmed identfication: |
1427828 1840704 15384081 16252232 |
| RefSeq identity: |
NM_030751 |
| Classification: |
ZF class homeoboxes and pseudogenes Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000017907 |