| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
2, Zinc finger E-box-binding homeobox 1 & |
| Specificity: |
This antibody reacts specifically with ZEB |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ZEB1 |
| Gene ID: |
6935, 9839 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type, May be responsible for transcriptional repression of the IL-2 gene, Promotes tumorigenicity by repressing stemness-inhibiting microRNAs, Represses BCL6 transcription in the presence of the corepressor CTBP1, Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1, Inhibits interleukin-2 (IL-2) gene expression |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BZP ZEB AREB6 NIL-2-A Zfhep Zfhx1a FECD6 |
| Also known as: |
ZEB Polyclonal Antibody |
| Other name: |
Anti-ZEB Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ZEB |
| Short name: |
Anti-ZEB (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ZEB (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11642 |
| Gene: |
ZEB1 |
More about : ZEB1 |
| Long gene name: |
zinc finger E-box binding homeobox 1 |
| Synonyms gene: |
TCF8 PPCD3 |
| Synonyms gene name: |
transcription factor 8 (represses interleukin 2 expression) posterior polymorphous corneal dystrophy 3 |
| Locus: |
10p11, 22 |
| Discovery year: |
1991-12-17 |
| GenBank acession: |
AK091478 |
| Entrez gene record: |
6935 |
| Pubmed identfication: |
1427828 1840704 15384081 16252232 |
| RefSeq identity: |
NM_030751 |
| Classification: |
ZF class homeoboxes and pseudogenes Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000017907 |