| Long name: |
ZEB Primary Polyclonal Antibody |
| Also known as: |
ZEB PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
2, Zinc finger E-box-binding homeobox 1 & |
| Specificity: |
2, This is a highly specific antibody against Zinc finger E-box-binding homeobox 1 & |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
210-260/1124 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZEB1 |
| Gene ID number: |
6935, 9839 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type, May be responsible for transcriptional repression of the IL-2 gene, Promotes tumorigenicity by repressing stemness-inhibiting microRNAs, Represses BCL6 transcription in the presence of the corepressor CTBP1, Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1, Inhibits interleukin-2 (IL-2) gene expression |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AREB6, BZP, DELTA EF1, Delta crystallin enhancer binding factor 1, FECD6, MGC133261, NIL 2 A, NIL 2 A zinc finger protein, NIL 2A, NIL-2-A zinc finger protein, NIL2A, Negative regulator of IL 2, Negative regulator of IL2, PPCD3, Posterior polymorphous corneal dystrophy 3, Represses interleukin 2 expression, TCF 8, TCF-8, TCF8, Transcription factor 8, Transcription factor 8 represses interleukin 2 expression, ZEB, ZEB 1, ZEB1, ZEB1_HUMAN, ZFHEP, ZFHX 1A, ZFHX1A, Zinc finger E box binding homeobox 1, Zinc finger E-box-binding homeobox 1, Zinc finger homeodomain enhancer binding protein, AREB 6 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ZEB |
| Short name: |
ZEB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ZEB (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11642 |
| Gene: |
ZEB1 |
More about : ZEB1 |
| Long gene name: |
zinc finger E-box binding homeobox 1 |
| Synonyms gene: |
TCF8 PPCD3 |
| Synonyms gene name: |
transcription factor 8 (represses interleukin 2 expression) posterior polymorphous corneal dystrophy 3 |
| Synonyms: |
BZP ZEB AREB6 NIL-2-A Zfhep Zfhx1a FECD6 |
| Locus: |
10p11, 22 |
| Discovery year: |
1991-12-17 |
| GenBank acession: |
AK091478 |
| Entrez gene record: |
6935 |
| Pubmed identfication: |
1427828 1840704 15384081 16252232 |
| RefSeq identity: |
NM_030751 |
| Classification: |
ZF class homeoboxes and pseudogenes Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000017907 |