| Catalog number: | bs-4182R-Cy5.5 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | RPA32 Antibody, Cy5.5 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy5, 5 Conjugated, RPA32 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Cy5, 5, 5, Cy5 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | RPA32 |
| Specificity: | This is a highly specific antibody against RPA32 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen_range: | 110-160/270 |
| Subcellular location: | Nucleus |
| Source: | KLH conjugated synthetic peptide derived from human RPA32/RPA2 |
| Gene ID number: | 6118 |
| Swiss Prot: | P15927 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Also recruits SMARCAL1/HARP, Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair, In the cellular response to DNA damage, It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage, It prevents their reannealing and in parallel, May also play a role in telomere maintenance, Plays also a role in base excision repair (BER) probably through interaction with UNG, Thereby, Through RFWD3 may activate CHEK1 and play a role in replication checkpoint control, Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response, binds and stabilizes single-stranded DNA intermediates, it plays an essential role both in DNA replication and the cellular response to DNA damage, recruits and activates different proteins and complexes involved in DNA metabolism, that form during DNA replication or upon DNA stress, the RPA complex controls DNA repair and DNA damage checkpoint activation, to sites of DNA damage, which is involved in replication fork restart, As part of the heterotrimeric replication protein A complex (RPA/RP-A) |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 675nm/694nm |
| Synonyms: | RF-A protein 2, RP-A p32, RP-A p34, RPA2, RPA32, RPA34, Replication factor A protein 2, Replication protein A 32 kDa subunit, Replication protein A 34 kDa subunit, REPA2 |
| Properties: | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: | RPA32 Conjugated |
| Short name: | Conjugated, RPA32 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | 5, Cy5 |
| Alternative name: | cyanine 5, 5 coupled, RPA32 (Antibody to) |
| Alternative technique: | antibodies |
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