| Long name: |
PPAR alpha (Ser12) Primary Polyclonal Antibody |
| Also known as: |
PPAR alpha (Ser12) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PPAR alpha Ser12 |
| Specificity: |
This is a highly specific antibody against PPAR alpha Ser12 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser12 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-15/468 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human PPAR alpha around the phosphorylation site of ser12 |
| Gene ID number: |
5465 |
| Swiss Prot: |
Q07869 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activated by oleylethanolamide, Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC), Functions as transcription activator for the ACOX1 and P450 genes, Key regulator of lipid metabolism, May be required for the propagation of clock information to metabolic pathways regulated by PER2, Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids, Regulates the peroxisomal beta-oxidation pathway of fatty acids, Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2, a naturally occurring lipid that regulates satiety, Ligand-activated transcription factor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
NR1C1, Nuclear receptor subfamily 1 group C member 1, PPAR-alpha, PPARA, PPARalpha, Peroxisome proliferator-activated receptor alpha, hPPAR, PPAR |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PPAR alpha (Ser12) |
| Short name: |
PPAR alpha (Ser12) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PPAR a (Ser12) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9232 |
| Gene: |
PPARA |
More about : PPARA |
| Long gene name: |
peroxisome proliferator activated receptor alpha |
| Synonyms gene: |
PPAR |
| Synonyms gene name: |
alpha peroxisome proliferator-activated receptor alpha , peroxisome proliferative activated receptor |
| Synonyms: |
hPPAR NR1C1 |
| Locus: |
22q13, 31 |
| Discovery year: |
1993-11-01 |
| GenBank acession: |
L02932 |
| Entrez gene record: |
5465 |
| Pubmed identfication: |
7684926 10591208 |
| RefSeq identity: |
NM_001001928 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000150443 |