| known also as: |
Anti-RABBIT ANTI HUMAN PPAR ALPHA (N-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN PPAR ALPHA (N-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens PPAR ALPHA (N-TERMINAL) |
| known also as: |
PPAR ALPHA |
| Other names: |
Nuclear receptor subfamily 1 group C member 1, PPAR-alpha, Peroxisome proliferator-activated receptor alpha, alpha, nuclear receptor subfamily 1 group C member 1, peroxisome proliferative activated receptor, peroxisome proliferator-activated nuclear receptor alpha variant 3, peroxisome proliferator-activated receptor alpha, peroxisome proliferator-activated receptor alpha, peroxisome proliferator-activated receptor alpha |
| Gene name: |
PPAR ALPHA |
| Other gene names: |
NR1C1, NR1C1, PPAR, PPAR, PPAR-alpha, PPARA, PPARalpha, hPPAR, PPARA |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
In particular, PPARA controls genes involved in the peroxisomal and mitochondrial beta oxidation pathways, PPARA forms heterodimers with retinoid X receptors (RXRs), They could also be used for the treatment of type II diabetes, Upon activation, _x000D__x000D_PPARA also has anti-inflammatory and anti-proliferative effects and prevents the proatherogenic effects of cholesterol accumulation in macrophages by stimulating cholesterol efflux, _x000D__x000D_PPARA is the main target of fibrate drugs, a member of the nuclear hormone receptor subfamily, alpha (PPARA), and functions to regulate transcription of specific gene sequences, and triglyceride catabolism in the liver and skeletal muscle, fatty acid uptake, hypolipidemic agents used in the treatment of dyslipidemia and the prevention of cardiovascular disease, PPAR ALPHA This item detects an epitope within the N-terminal region of human peroxisome proliferator-activated receptor |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
PPAR ALPHA |
| Short name: |
Anti-HUMAN PPAR ALPHA (N-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens PPAR a (N-TERMINAL) (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
9232 |
| Gene: |
PPARA |
More about : PPARA |
| Long gene name: |
peroxisome proliferator activated receptor alpha |
| Synonyms gene: |
PPAR |
| Synonyms gene name: |
alpha peroxisome proliferator-activated receptor alpha , peroxisome proliferative activated receptor |
| Synonyms: |
hPPAR NR1C1 |
| Locus: |
22q13, 31 |
| Discovery year: |
1993-11-01 |
| GenBank acession: |
L02932 |
| Entrez gene record: |
5465 |
| Pubmed identfication: |
7684926 10591208 |
| RefSeq identity: |
NM_001001928 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000150443 |