| Long name: |
Cy5, 5 Conjugated, PFKL (Ser775) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PFKL Ser775 |
| Specificity: |
This is a highly specific antibody against PFKL Ser775 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser775 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human PFKL around the phosphorylation site of Ser775 |
| Gene ID number: |
5211 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Mammalian PFK is a tetramer made up of diverse combinations of three isoenzymes: muscle (PFK-1), Overexpression of PFKL in transgenic mice results in a diminished glucose-induced insulin response, PFKL (phosphofructokinase, PFKL is expressed at high levels in Down's syndrome (DS) patients, also referred to as PFK-B (Phosphofructo-1-kinase isozyme B), liver (PFKL) and platelet (PFKP), liver), phosphofructokinase 1 or phosphohexokinase, predominates in organs with active gluconeogenesis, such as liver and kidney, suggesting a possible role for PFKL in the pathogenesis of DS, which suggests that PFKL may play a role in glucose-induced insulin secretion, 6-bisphosphate, Phosphofructokinases (PFKs) are regulatory glycolytic enzymes that catalyze the irreversible conversion of fructose-6-phosphate to fructose-1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
PFKL (Ser775) Conjugated |
| Short name: |
Conjugated, PFKL (Ser775) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, PFKL (Ser775) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8876 |
| Gene: |
PFKL |
More about : PFKL |
| Long gene name: |
liver type , phosphofructokinase |
| Locus: |
21q22, 3 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
5211 |
| Havana BLAST/BLAT: |
OTTHUMG00000086910 |